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Prodromal Alzheimers Disease: Successive Emergence of the Clinical Symptoms
Ann Neurol 64:492-498,479, Amieva,H.,et al, 2008
See this aricle in Pubmed

Article Abstract
This approach, describing the 14 years preceding dementia, provides a clear illustration of the particularly long and progressive prodromal phase of AD, and shows the successive emergence of cognitive deficits, depressive symptoms, and functional impairment during this phase.
 
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Alzheimer's disease
Alzheimer's disease,preclinical
asymptomatic
dementia,early detection
depression
heralding manifestation
memory,impairment of
preclinical
psychological testing

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